Easy and effective therapy to restore sight: Engineered virus will improve gene therapy for blinding eye diseases
Gene therapy using adeno-associated virus has successfully restored sight to people with a rare inherited retinal degeneration, but current therapy requires injecting the virus directly into the retina. Researchers have now caused AAV to evolve so that it is able to penetrate the retina, allowing doctors to inject the virus and its gene load into the vitreous to reach all cells of the retina. This broadens AAV's potential application to more common types of vision loss.
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