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Neuroscientists identify class of cortical inhibitory neurons specializing in disinhibition

New research reveals that one class of inhibitory neurons -- called VIP interneurons -- specializes in inhibiting other inhibitory neurons in multiple regions of cortex, and does so under specific behavioral conditions. The new research finds that VIP interneurons, when activated, release principal cells from inhibition, thus boosting their responses. This provides an additional layer of control over cortical processing, much like a dimmer switch can fine-tune light levels.
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