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Researchers discover, treat toxic effects of ALS mutation in neurons using patients' skin cells

Researchers have discovered how the most common genetic abnormality in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia kills neurons, and have successfully developed a therapeutic strategy to block this neurodegeneration in neurons made from the skin cells of ALS patients. The findings have important implications for treating patients with these debilitating, currently incurable neurodegenerative diseases.
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