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Pediatric patients most likely to have long-term damage from prolonged seizures

A long-standing hypothesis holds that prolonged febrile (fever induced) seizures (PFS), the most common form of childhood convulsive status epilepticus (CSE), cause mesial temporal sclerosis (MTS). Whether prolonged convulsions lead to long-term damage to hippocampus or MTS is uncertain. A team of investigators looking into this question has found that a subgroup, and not all, children who experience CSE have impaired hippocampal growth years after the prolonged seizure.
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