Can a protein controlling blood pressure enhance immune responses and prevent Alzheimer's?
Many people with high blood pressure are familiar with ACE inhibitors, drugs that widen blood vessels by limiting activity of ACE ? angiotensin-converting enzyme ? a naturally occurring protein found in tissues throughout the body. But high activity of the enzyme ? in the right context, place and time ? may be a good thing. A study found that genetically targeting certain immune blood cells to overproduce the enzyme broke down defective proteins in the brain associated with Alzheimer's disease and prevented cognitive decline in laboratory mice bred to model the disease.
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