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Understanding basic biology of bipolar disorder

Instead of only using a standard clinical interview to determine whether individuals met the criteria for a clinical diagnosis of bipolar disorder, researchers combined the results from brain imaging, cognitive testing, and an array of temperament and behavior measures. Using the new method, they and their collaborators have identified about 50 brain and behavioral measures that are both under strong genetic control and associated with bipolar disorder. Their discoveries could be a major step toward identifying the specific genes that contribute to the illness.
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