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First biological marker for major depression could enable better diagnosis, treatment

Teenage boys who show a combination of depressive symptoms and elevated levels of the 'stress hormone' cortisol are up to fourteen times more likely to develop major depression than those who show neither trait, according to research. Major, or clinical, depression is a debilitating mental health problem that will affect one in six people at some point in their lives. However, until now there have been no biomarkers for major depression; this is believed to be, in part, because both the causes and the symptoms can be so varied.
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