Dangerous mistaken identity: Protein folding leads to some neurodegenerative diseases
Tau proteins, which are responsible for Alzheimer's disease, bind to the folding protein HSP90. The molecular recognition mechanisms that play a role here have been unveiled by an international team of scientists, and may open the door for new approaches for the treatment of Alzheimer's disease and further neurodegenerative diseases that are caused by protein aggregation. These scientific insights provide an important basis for better understanding these disease mechanisms.
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