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Study to Determine if Vitamin D Supplements Will Improve Mood in Women with Type 2 Diabetes

Researchers are recruiting women for a study to determine whether raising blood levels of vitamin D can improve mood in women with diabetes. The study also will examine whether raising vitamin D levels can reduce blood pressure and affect how well women manage their diabetes. The study will explore whether vitamin D supplementation decreases inflammation, thus providing evidence for a plausible mechanism for how the vitamin works as an antidepressant. About 1 in 10 people in the United States has diabetes, and the incidence is projected to increase to 1 in 4 persons by 2050. Women with type 2 diabetes have worse outcomes than men. The reason may be due to depression, which affects more than 25 percent of women with diabetes. Depression impairs a patient's ability to manage her disease.
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