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Brain, cognitive reserve protect long-term against cognitive decline, MS researchers find

MS researchers have found brain reserve and cognitive reserve confer long-term protective effect against cognitive decline. In this study, memory, cognitive efficiency, vocabulary (a measure of intellectual enrichment/cognitive reserve), brain volume (a measure of brain reserve), and disease progression on MRI, were evaluated in 40 patients with MS at baseline and at 4.5-year followup. After controlling for disease progression, scientists looked at the impact of brain volume and intellectual enrichment on cognitive decline.
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