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African American women more resistant to anti-inflammatory effect of aspirin than white women

African American women respond differently to the anti-inflammatory effect of aspirin than do white American women, new research finds. Even though African American women have higher high-density lipoprotein (HDL, the "good" cholesterol) and lower triglyceride levels, they also have increased insulin resistance, oxidative stress burden, proinflammatory markers, HDL dysfunctionality -- and significantly higher mortality. Aspirin therapy has been recommended to reduce subclinical atherosclerosis and cardiovascular disease outcomes, including stroke.
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