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Dementia risk quadrupled in people with mild cognitive impairment

In a long-term, large-scale population-based study of individuals aged 55 years or older in the general population, researchers found that those diagnosed with mild cognitive impairment (MCI) had a four-fold increased risk of developing dementia or Alzheimer?s disease (AD) compared to cognitively healthy individuals. Several risk factors including older age, positive APOE-?4 status, low total cholesterol levels, and stroke, as well as specific MRI findings were associated with an increased risk of developing MCI.
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