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Focal blood-brain-barrier disruption with high-frequency pulsed electric fields

A novel method uses bursts of nanosecond duration electric pulses to open the blood-brain-barrier as a potential therapy for brain cancer and neurological disorders. The Vascular Enabled Integrated Nanosecond pulse (VEIN pulse) procedure consists of inserting minimally invasive needle electrodes into the diseased tissue and applying multiple bursts of nanosecond pulses with alternating polarity.
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